Self-assembly of organic semiconductor nanostructures via organic solid-solid wetting deposition. Organic Semiconductor Group Dr. Frank Trixler
Organic Semiconductor
          Group Dr. Trixler
Prebiotic Chemistry in Nanoscale Confinements

 
Scanning Tunneling Microscopy image of self-assembled acridone molecules on graphite, grown via OSWD. Nanochain width: 1,0 nm. © F. Trixler.


A central issue in the research on the emergence of life is the paradoxical role of water in prebiotic chemistry. On the one hand, water is essential for all known life, on the other hand it is highly destructive for key biomolecules such as nucleic acids and polypeptides.

We investigate the possible relevance of nanoscale phenomena and nanofluidic effects for prebiotic chemistry to solve key paradoxes in the research on the origin of life. For this investigations we use OSWD as an analytical probe, along with approaches established in molecular biology.


Selected publications:

Temporal nanofluid environments induce prebiotic condensation in water
A. Greiner de Herrera, T. Markert and F. Trixler
Commun. Chem. 6, 69 (2023).
DOI: 10.1038/s42004-023-00872-y [pdf]

Origin of Nucleic Acids
F. Trixler
In: A. Neubeck, S. McMahon (eds): Prebiotic Chemistry and the Origin of Life.
Springer Nature (2021).
DOI: 10.1007/978-3-030-81039-9_5 [pdf]


Quantum Tunnelling to the Origin and Evolution of Life.
F. Trixler,
Current Organic Chemistry 17(16), 1758-1770 (2013).
DOI: 10.2174/13852728113179990083
[pdf]